If you meet the criteria to get into the Express Entry pool: Yes. If you are 47 or over, you will not get any points under the Age factor of the Comprehensive Ranking System, but you may get points for other factors such as a job offer, your skills, your language abilities, etc. You may still be invited to apply based on your CRS score and your rank in the pool.
If you receive an Invitation to Apply for permanent residence through the Express Entry system under the FSW program: Yes. If you are over 47, you will not get any points under the Age factor of the FSW selection grid, but you can still apply. The applicant's age is worth 12 percent of the overall selection criteria on the FSW selection grid.
Note: Completing an Express Entry profile is the first step to immigrate to Canada permanently as a federal skilled worker. Completing an Express Entry profile does not guarantee that you will receive an Invitation to Apply for permanent residence. An Invitation to Apply for permanent residence will be based on your score and rank in the Express Entry pool using the Comprehensive Ranking System.