Generally, yes. Your study permit must still be valid and you must still meet all the requirements.
If you work off-campus
You can work full-time during scheduled breaks, like over summer holidays and during spring break. You must meet all the requirements for working off-campus before you start working. Once your school year restarts, you can only work a maximum of 20 hours per week.
If you work on-campus
You can work full-time during scheduled breaks, like over summer holidays and during spring break. You must meet all the requirements for working on-campus before you start working.